疏风解毒胶囊佐治慢性阻塞性肺疾病急性加重期伴肺部感染的临床观察

李迅

（医院呼吸内科，安徽）

摘要：目的：观察疏风解毒胶囊在治疗慢性阻塞性肺疾病急性加重期（AECOPD）伴肺部感染的临床治疗效果。方法:将本院收治的伴肺部感染的AECOPD患者按照入院时间随机纳入对照组与治疗组，各50例。对照组予头孢曲松抗感染治疗，治疗组同时予以疏风解毒胶囊治疗。两组患者同时按AECOPD处理治疗。观察两组患者治疗期间咳嗽、咳痰、肺部啰音变化变化情况，以及治疗前、治疗第3、10天超敏C反应蛋白（hs-CRP）、降钙素原（PCT）、肺部感染评分（CPIS）变化情况，对临床治疗效果进行评价分析。结果：治疗组患者咳嗽、咳痰、肺部啰音平均消失时间小于对照组（P＜0.05）。治疗3d、10d后，治疗组hs-CRP、PCT、CPIS指标低于对照组（P＜0.05），其中治疗组hs-CRP、PCT基本恢复正常参考值水平；治疗组患者有效率大于对照组（P＜0.05）。结论：联合疏风解毒胶囊治疗能够加快伴肺部感染的AECOPD患者肺部感染控制，促进患者恢复。

关键词：疏风解毒胶囊；慢性阻塞性肺疾病急性加重期；肺部感染；临床观察；联合用药

ClinicalobservationofShufengJieduCapsuleinthetreatmentofacuteexacerbationofchronicobstructivepulmonarydiseasewithpulmonaryinfection

LiXun

（RespiratoryDepartment,ThefirstPeoplesHospitalofChuzhou,Chuzhou,China）

Abstract:Objective:ToobserveclinicalcurativeeffectiveofShufengJieduCapsuleinthetreatmentofacuteexacerbationofchronicobstructivepulmonarydisease(AECOPD)withpulmonaryinfection.Methods:OnehundredpatientswithAECOPDwithpulmonaryinfectionweredividedintocontrolgroupandtreatmentgroup,50casesineachgroup.Thecontrolgroupwasgivenceftriaxone,thetreatmentgroupwasgivenShufengJieduCapsulebesidesoftheCeftriaxone.Thecourseoftreatmentwas10days.Theclinicalsymptomsandsigns(cough,sputum,pulmonaryrales),contentchangesofhypersensitivec-reactiveprotein(hs-CRP)andcalcitonin(PCT)inbloodandpulmonaryinfectionscore(CPIS)wereobservedafterthetreatmentfor3daysor10days.Results:Thecardinalsymptomsandsignsofrecoverytimeoftreatmentgroupwerelessthanthoseofcontrolgroup(P0.05),andthehs-CRPandPTCandCPISwerelessthancontrolgroupafterthetreatmentfor3daysand10days(P0.05).Thetotleeffectiverateofthetreatmentgroupwerebetterthanthatofthecontrolgroup(P0.05).ConclusionShufengJieduCapsulecouldrelieveAECOPDwithpulmonaryinfection，andpromoteclinicalrecovery.

Keywords:ShufengJieduCapsule;Cuteexacerbationofchronicobstructivepulmonarydisease;Pulmonaryinfection;Clinicalobservation;Drug